Molinski, Steven V : rechercher sur Z-Library

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1

Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2018

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2018

2

Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells

Rukhsana Aslam, Michael Kim, Edwin R. Speck, Arjuna Contram Seetanah, Steven Molinski, John Freedman, John W. Semple

Journal:

Transfusion (Wiley)

Année:

2007

Langue:

english

Fichier:

PDF, 275 KB

english, 2007

3

Reductive Dechlohnation of Dysidenin from Dysidea Herbacea . Structure of a Novel Binuclear Zinc Metallocycle

Trousdale, Eugene K., Taylor, Steven W., Parkin, Sean, Hope, Håkon, Molinski, Tadeusz F.

Journal:

Natural Product Letters

Année:

1998

Langue:

english

Fichier:

PDF, 362 KB

english, 1998

4

VX-809 and Related Corrector Compounds Exhibit Secondary Activity Stabilizing Active F508del-CFTR after Its Partial Rescue to the Cell Surface

Eckford, Paul D.W., Ramjeesingh, Mohabir, Molinski, Steven, Pasyk, Stan, Dekkers, Johanna F., Li, Canhui, Ahmadi, Saumel, Ip, Wan, Chung, Timothy E., Du, Kai, Yeger, Herman, Beekman, Jeffrey, Gonska,

Journal:

Chemistry & Biology

Année:

2014

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2014

5

Exact Mass Determination for Elemental Analysis of Ions Produced by Matrix-Assisted Laser Desorption

Wu, Jiangyue., Fannin, Steven T., Franklin, Melanie A., Molinski, Tadeusz F., Lebrilla, Carlito B.

Journal:

Analytical Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 514 KB

english, 1995

6

Oxidation of Peptidyl 3,4-Dihydroxyphenylalanine Analogues: Implications for the Biosynthesis of Tunichromes and Related Oligopeptides

Taylor, Steven W., Molinski, Tadeusz F., Rzepecki, Leszek M., Waite, J. Herbert

Journal:

Journal of Natural Products

Année:

1991

Langue:

english

Fichier:

PDF, 327 KB

english, 1991

7

Genetic, cell biological, and clinical interrogation of the CFTR mutation c.3700 A>G (p.Ile1234Val) informs strategies for future medical intervention

Molinski, Steven V., Gonska, Tanja, Huan, Ling Jun, Baskin, Berivan, Janahi, Ibrahim A., Ray, Peter N., Bear, Christine E.

Journal:

Genetics in Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2014

8

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation

Pasyk, Stan, Molinski, Steven, Ahmadi, Saumel, Ramjeesingh, Mohabir, Huan, Ling-Jun, Chin, Stephanie, Du, Kai, Yeger, Herman, Taylor, Paul, Moran, Michael F., Bear, Christine E.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

9

Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5

D’Antonio, Christina, Molinski, Steven, Ahmadi, Saumel, Huan, Ling‑Jun, Wellhauser, Leigh, Bear, Christine E.

Journal:

Biochemical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 921 KB

english, 2013

10

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Pasyk, Stan, Molinski, Steven, Yu, Wilson, D.W. Eckford, Paul, E. Bear, Christine

Journal:

Current Pharmaceutical Design

Année:

2012

Langue:

english

Fichier:

PDF, 933 KB

english, 2012

11

The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain

Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E.

Journal:

Biochemical Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2016

12

Attenuation of Phosphorylation-dependent Activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Disease-causing Mutations at the Transmission Interface

Chin, Stephanie, Yang, Donghe, Miles, Andrew J., Eckford, Paul D. W., Molinski, Steven, Wallace, B. A., Bear, Christine E.

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2017

13

Computational proteome-wide screening predicts neurotoxic drug-protein interactome for the investigational analgesic BIA 10-2474

Molinski, Steven V., Shahani, Vijay M., MacKinnon, Stephen S., Morayniss, Leonard D., Laforet, Marcon, Woollard, Geoffrey, Kurji, Naheed, Sanchez, Cecilia G., Wodak, Shoshana J., Windemuth, Andreas

Journal:

Biochemical and Biophysical Research Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2017

14

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

Ahmadi, Saumel, Bozoky, Zoltan, Di Paola, Michelle, Xia, Sunny, Li, Canhui, Wong, Amy P., Wellhauser, Leigh, Molinski, Steven V., Ip, Wan, Ouyang, Hong, Avolio, Julie, Forman-Kay, Julie D., Ratjen, Fe

Journal:

npj Genomic Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2017

15

Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue

Molinski, Steven V, Ahmadi, Saumel, Ip, Wan, Ouyang, Hong, Villella, Adriana, Miller, John P, Lee, Po‐Shun, Kulleperuma, Kethika, Du, Kai, Di Paola, Michelle, Eckford, Paul DW, Laselva, Onofrio, Huan,

Journal:

EMBO Molecular Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 4.74 MB

english, 2017

16

The Antiretroviral nelfinavir mesylate, a potential therapy for systemic scleroderma

Sanchez, Cecilia G., Molinski, Steven V., Gongora, Rafael, Sosulski, Meredith, Fuselier, Taylor, MacKinnon, Stephen S., Mondal, Debasis, Lasky, Joseph A.

Journal:

Arthritis & Rheumatology

Année:

2017

Langue:

english

Fichier:

PDF, 3.68 MB

english, 2017

17

Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains

Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E.

Journal:

Molecular Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 3.65 MB

english, 2018

18

Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins

Molinski, Steven V., Bozóky, Zoltán, Iram, Surtaj H., Ahmadi, Saumel

Journal:

International Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.83 MB

english, 2017

19

Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics

Hernandez, J. Javier, Pryszlak, Michael, Smith, Lindsay, Yanchus, Connor, Kurji, Naheed, Shahani, Vijay M., Molinski, Steven V.

Journal:

Frontiers in Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 458 KB

english, 2017

20

Functional Rescue of F508del-CFTR Using Small Molecule Correctors

Molinski, Steven, Eckford, Paul D. W., Pasyk, Stan, Ahmadi, Saumel, Chin, Stephanie, Bear, Christine E.

Journal:

Frontiers in Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2012

21

Cover Image, Volume 86, Issue 8

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2018

Fichier:

PDF, 1.31 MB

2018

22

Patterns of Ellipsis in Russian Compound Noun Formations || Examples cited have been taken from the following sources

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 159 KB

1973

23

Patterns of Ellipsis in Russian Compound Noun Formations || Introduction

Molinsky, Steven J.

Année:

1973

Langue:

english

Fichier:

PDF, 319 KB

english, 1973

24

Patterns of Ellipsis in Russian Compound Noun Formations || Introduction

Molinsky, Steven J.

Année:

1973

Langue:

english

Fichier:

PDF, 298 KB

english, 1973

25

Patterns of Ellipsis in Russian Compound Noun Formations || Introduction

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 298 KB

1973

26

Patterns of Ellipsis in Russian Compound Noun Formations || IV. Non-Reformulation of Oblique Complements

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 877 KB

1973

27

Patterns of Ellipsis in Russian Compound Noun Formations || Appendix: Athematic Partial Truncations

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 1.37 MB

1973

28

Patterns of Ellipsis in Russian Compound Noun Formations || I. Non-Oblique Underlying Phrases of a Structure [X-Y]

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 1.93 MB

1973

29

Patterns of Ellipsis in Russian Compound Noun Formations || IV. Borrowed Compound Patterns in Twentieth Century Russian

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 987 KB

1973

30

Patterns of Ellipsis in Russian Compound Noun Formations || III. Borrowings from Western European Languages into Russian

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 900 KB

1973

31

Patterns of Ellipsis in Russian Compound Noun Formations || II. The Historical Basis of Thematic Compound Formation: Early Borrowings from Greek

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 1.24 MB

1973

32

Patterns of Ellipsis in Russian Compound Noun Formations || I. Typology of Inherited Thematic Compound Formations in Modern Russian

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 2.04 MB

1973

33

Patterns of Ellipsis in Russian Compound Noun Formations || V. Non-Compounded (Simple) Truncations

Molinsky, Steven J.

Année:

1973

Fichier:

PDF, 202 KB

1973